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AEROSPAN (flunisolide) Inhalation Aerosol is the only ICS available with a built-in spacer3

68.3% of the dose gets into the lungs4,5

  • The relationship of lung deposition to clinical efficacy is unknown
  • Single-dose scintigraphy trial in 12 healthy subjects; results represent average lung deposition4,5
    • —  Image below is from a representative subject4
    • —  Healthy subjects were taught to inhale slowly and deeply and the investigator actuated radiolabeled MDI of flunisolide HFA about 1 second after subject started to inhale5
Scintigraphy image showing lung deposition of AEROSPAN
  • AEROSPAN offers a small particle size, averaging 1.2 μm,* and a built-in spacer to enhance lung deposition6
Mass median aerodynamic diameter (MMAD): The diameter of the particle at the median within the range of weights of aerodynamic particles.
Image reproduced with permission from J Allergy Clin
Immunol
. 2002;109(2 suppl):S457.4
  • Flunisolide is not a prodrug and does not need to be metabolized to a more active form
Mass median aerodynamic diameter (MMAD): The diameter of the particle at the median within the range of weights of aerodynamic particles.